Cyclopam Syrup Dose For Child

Cyclopam Syrup Dose for Child

Hello, today we will discuss the Cyclopam Syrup Dose For Children. Cyclopam Suspension is composed of Dicyclomine and Simethicone. It treats numerous stomach problems, such as bloating, cramping, belching, and other gastrointestinal problems (disorders of the stomach and intestines).

Overview 

Price: ₹65.9

Quantity: 30 ml

Consume Type: Oral

Contains: Dicycloverine / Dicyclomine(10.0 Mg/5ml) + Simethicone / Simeticone(40.0 Mg/5ml)

Manufactured By: INDOCO REMEDIES LTD

Therapy: ANTI-FLATULENT

Expires on: 29/09/2026

Uses: Abdominal pain, Colicky pains, irritable bowel syndrome

Side Effects: Dizziness, increased thirst, dry mouth

Pharmacological Classification

Component Drug Class Mechanism of Action
Dicyclomine Hydrochloride Anticholinergic (Antispasmodic) Blocks acetylcholine at parasympathetic sites in smooth muscle → reduces gastrointestinal motility and spasms
Simethicone Anti-flatulent Decreases surface tension of gas bubbles → promotes coalescence and easy gas elimination

Market Price Analysis (India – Pediatric Pack) of Cyclopam Syrup

Retail Pricing Benchmark (2024–2026)

Pack Size MRP (₹) Average Discounted Price (₹) Price per ml (₹) Market Availability
30 ml ₹61.78 – ₹67.00 ₹47.57 – ₹60.30 ₹1.59 – ₹2.01/ml High
60 ml ₹86.90 – ₹96.56 ₹73.31 – ₹86.90 ₹1.30 – ₹1.45/ml Moderate
  • Online pharmacy listings show 30 ml Cyclopam Suspension priced ~₹60.3 (₹2.01/ml).
  • Generic retail portals list MRP ₹61.78 with discounted selling price ₹47.57 for pediatric 30 ml pack.
  • Some pharmacy distributors offer ₹55.6 post-discount for 30 ml pack.
  • Offline chain pharmacies report ~₹60 retail price for 30 ml bottle.

Cost Efficiency Assessment

Pack Size Cost Efficiency Clinical Suitability
30 ml Pack Higher per ml cost Short-term colic management
60 ml Pack Lower per ml cost Recurrent IBS or chronic spasmodic pain

The 60 ml pediatric pack demonstrates ~25–35% lower cost-per-ml, making it economically preferable in prolonged antispasmodic therapy cycles.

Price Comparison with Therapeutic Alternatives

Pediatric Antispasmodic Suspension 30 ml MRP (₹) Avg. Selling Price (₹)
Cyclopam Suspension ₹61.78 ₹47 – ₹60
Colimex Suspension ₹69.00 ₹57 – ₹58
Meftal Spas Suspension (60 ml) ₹86.25 ₹73 – ₹77

Compositionally equivalent formulations (Dicycloverine + Simethicone) show a ~5–12% price premium compared to Cyclopam in Indian pediatric GI antispasmodic segment.

Dosage

Pediatric Dose Calculation Framework (Weight-Based)

Child Weight Recommended Dose Range Frequency Maximum Daily Dose
5–7 kg 2.5 ml 2–3 times daily 7.5 ml
7–12 kg 2.5–5 ml 2–3 times daily 10 ml
12–20 kg 5 ml 3 times daily 15 ml
20–30 kg 5–7.5 ml 3 times daily 20 ml

Pediatric dosing must be physician-guided. Dicyclomine has CNS penetration; therefore, overuse may lead to neurological adverse effects in children. (Apollopharmacy)

Missed Dose 

Give the missed dose of Cyclopam Suspension as soon as possible. Do not multiply your dosage to make up for the missed dose. If it is almost time for your next dose, skip the unused dose.

Overdose 

Seek medical emergency in case of Cyclopam Suspension overdose.

Indication-Based Pediatric Administration

Clinical Condition Therapeutic Goal Recommended Timing
Infantile Colic (≥6 months) Reduce intestinal spasms Before feeds
Functional Abdominal Pain Smooth muscle relaxation 20 min before meals
IBS-related pain Reduce motility & cramping Regular intervals
Gas retention Bubble dispersion After meals

Side Effects and Uses Of Cyclopam Syrup 

Side Effect Uses
Nausea and vomiting Colicky pains
Dry mouth Abdominal pain
Burping Irritable bowel syndrome
Loss of appetite
Dizziness
Skin rash
Constipation

 Description 

Cyclopam Suspension is composed of Dicyclomine and Simethicone. It treats numerous stomach problems like bloating, cramping, belching, and other gastrointestinal problems (disorders of the stomach and intestines).

Cyclopam Suspension is commonly used in infants (children up to one year) above six months of age. It works by relaxing the muscles of the stomach and intestines and easing gas passage.

Cyclopam Suspension shows side effects like constipation, burping, loss of appetite, nausea, and vomiting. Do not use this medicine if your child is allergic to it. Check with your doctor if the side effects persist or bother your child.

Cyclopam Suspension can cause drowsiness in your child. Hence, avoid activities that require mental attention while your child is taking this medicine.

Cyclopam Suspension is usually taken before food or as your child’s doctor instructs. Give this medicine at the same time every day so that a continuous level of medicine can be maintained in your child’s body. Do not stop giving this syrup without consulting your child’s doctor, as the symptoms may reoccur.

Cyclopam Suspension should be given with caution if your child has kidney or heart disorders. Inform your doctor about all your child’s current medications, including any herbs and supplements, as they can interact with this medicine and cause side effects.

Pharmacokinetics in Children

Parameter Dicyclomine Simethicone
Absorption Rapid oral absorption Not systemically absorbed
Onset of Action 1–2 hours Immediate local action
Metabolism Hepatic Not metabolized
Excretion Urinary Fecal (unchanged)
Half-Life ~1.8 hours N/A

Warnings

Cyclopam Suspension may cause severe skin allergies without any warnings. These events may be severe in rare cases. Signs and symptoms like rashes, hives, fever, or other allergic indications should remain informed to your doctor immediately. The treatment should be finished if these symptoms appear. (Pharmeasy)

Drowsiness

Cyclopam Suspension may cause sleepiness and dizziness in some children.

Use in children 

Cyclopam Suspension is not used in infants under 6 months as this medicine’s safety and efficacy data has not remained established in that age group.

Contraindications in Pediatric Population

  • Infants < 6 months
  • Obstructive uropathy
  • Severe ulcerative colitis
  • Reflux esophagitis
  • Myasthenia gravis
  • Narrow-angle glaucoma
  • Known hypersensitivity to anticholinergic drugs

Drug–Drug Interactions

Interacting Drug Type Potential Outcome
Antihistamines Enhanced anticholinergic effect
Tricyclic antidepressants Increased CNS depression
Antipsychotics Additive sedation
Opioids Reduced GI motility
Antacids Decreased absorption of dicyclomine

Monitoring Parameters During Therapy

Parameter Clinical Importance
Heart rate Tachycardia risk
Bowel movement frequency Constipation monitoring
Hydration status Risk of dry mouth
CNS response Drowsiness, irritability
Skin condition Allergic rash detection

Safety Risk Stratification

Risk Level Possible Adverse Event
Mild Dry mouth, nausea
Moderate Constipation, dizziness
Severe (Rare) Respiratory difficulty, seizures, skin hypersensitivity

Storage & Stability Guidelines

  • Store below 25°C
  • Protect from direct sunlight
  • Shake well before administration
  • Use within 30 days after opening
  • Keep away from freezing conditions

Therapeutic Alternatives to Cyclopam Syrup (Pediatric Use)

Therapeutic Alternatives to Cyclopam Syrup (Pediatric Use)

Brand Name Active Composition Pharmacological Class Pediatric Indication Minimum Age Use Key Difference from Cyclopam
Colimex Drops Dicyclomine + Simethicone Antispasmodic + Anti-flatulent Infantile colic, abdominal cramps ≥ 6 months Similar dual mechanism
Dicycloverine Oral Drops Dicycloverine HCl Anticholinergic Antispasmodic Functional abdominal pain ≥ 6 months No gas-dispersion effect
Simethicone Drops Simethicone Anti-flatulent Bloating, gas retention ≥ 1 month No smooth muscle relaxation
Colicaid Suspension Dill oil + Fennel oil + Simethicone Herbal Carminative + Anti-flatulent Mild colic & indigestion ≥ 1 month Non-anticholinergic formulation

Conclusion – Cyclopam Syrup Dose For Child

Lastly, we have provided all the information regarding Cyclopam Syrup Dose For Children. Let us know your feedback in the comment section below.